PAE Works - Prostatic Artery Embolization - 3rd Edition
Benign prostatic hyperplasia (BPH) is the most frequent cause of lower urinary tract symptoms (LUTS) in the aging male. It significantly alters quality of life (QoL), interfering with normal daily activities and sleep patterns. Moderate to severe LUTS will occur in about one quarter of men in their 50s, and in about half of all men aged 80 years or older. They consist of urinary frequency and urgency, nocturia, decreased and intermittent urinary stream and the sensation of incomplete bladder emptying. Complications of longstanding BPH include urinary calculi, infection, neurogenic bladder and complete bladder outlet obstruction (BOO).
Therapeutic options for patients with mild or moderate-grade symptoms include watchful waiting and medical or surgical therapies. Although long-term medical therapy can be effective, it is limited by significant side effects such as dizziness, orthostatic hypotension, ejaculatory or erectile dysfunction and decreased libido. Often, medical therapy can not be maintained for long periods of time because of compliance, cost, significant drug interactions, and ultimately, lack of efficacy.
For more than 80 years, transurethral resection of the prostate (TURP) has been considered as the gold standard surgical treatment for BPH. Investigators have been seeking other less invasive and durable therapies for BPH-related symptoms; one of the newest approaches has been prostatic artery embolization (PAE). Although TURP is associated with both better urodynamic results and more adverse events, both methods TURP and PAE are safe and effective treatments. At short- and medium-term, TURP and PErFecTED PAE yield similar symptom improvement.
PAE is a promising, minimally invasive alternative treatment for LUTS attributed to BPH that has shown to provide improvement in urinary flow rates, prostate volume, and QoL in many reports.
PAE Works was created and organized to facilitate the student learning through a theoretical (classes) and practical (simulation and live cases) approach to steadily expand the knowledge in the field of PAE treatment. Some important subjects as well as patient selection and basic technical principles are going to be discussed.
The pioneering experience of Prof. Dr. Francisco Carnevale and his group will be shared in detail with participants.
Radiology Institute - InRad – HCFMUSP
Francisco Carnevale, MD, PhD, Airton Mota Moreira MD, PhD and Andre Moreira de Assis, MD, PhD.